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Archive for June, 2008

Kevin Burkhart Jumps 100 Times for Parkinson’s Disease

Friday, June 6th, 2008

skydiving I first heard about Kevin Burkart’s aspirations to jump 100 times in one day back in January. I posted an article about him back in January. For months I have been anxiously anticipating this endeavor. I’ve heard of this being done before, but I am amazed that somebody can pull it off. I mean lets break this down a little bit and put it in perspective. Each jump requires obvious precision, discipline, and endurance. For each jump a parachute needs to be ready for the jump, now I’m not sure how many he officially used, but I’m guessing he probably used no more than 20, I could definitely be wrong here. If he did use only 20 then he would have to use a some kind of a ground crew to repack his parachute over and over until he hit jump 100. News sources state that in order for him to pull off this feat he will have to jump every 6 to 8 minutes!

Good thing Kevin wasn’t alone, many people were involved in his 100 jumps: two pilots, a cab crew, a grounds crew, volunteers, and of course news agents. I’m sure this kind of event can be compared to a marathon, but a little more difficult, because it’s not exactly financially feasible to train for something like this. Kevin mentioned in a news article that the most jumps he has ever done was 12 in a day… yikes. So I guess most of his physical preparation had to take place in a gym or running the streets of the twin cities area.

Anyways, I’m proud of Kevin and just wanted to write this thanking him for his dedication, heart, and hard-work for Parkinson’s disease. I hope my readers will take some time and thank him as well, you can reach his blog by clicking here.

Pedunculopontine nucleus is the focus for deep brain stimulation

Thursday, June 5th, 2008

Deep Brain Stimulation The pedunculopontine nucleus is a new target for deep brain stimulation in Parkinson’s patients, especially that that have had trouble with their stride and postural instability refractory.  This part of the brain is very much unknown for neurosurgeons, so the recent focus will be interesting to flush out.  We’ll keep you updated as we hear how deep brain stimulation of the pedunuculopontine nucleus goes.

Drug Reduces Tremors, Tics, and Spasms

Wednesday, June 4th, 2008

I just read this article from Forbes and thought I would pass it on to everyone.

MONDAY, June 2 (HealthDay News) — A new drug may help people with Parkinson’s disease combat the tics, spasms and tremors they experience when their main medications wear off, a new study suggests.

Istradfeylline works by helping nerve and brain signals bypass the damaged dopamine system in the brain that leads to Parkinson’s. A study of 395 Parkinson’s patients on levodopa, a popular Parkinson’s drug, found those using istradefylline experienced 24 percent less “off” time, defined as when the physical symptoms appear after levodopa wears off. A group of those studied who took a placebo showed a 10 percent decrease in “off” time.

“These results suggest that istradefylline is effective as an add-on therapy to other drugs that treat symptoms of Parkinson’s disease. More importantly, this medication seems to improve ‘off’ time in a population in which more than 90 percent of patients are already being treated with two or more drugs,” study author Dr. Mark Stacy, of Duke University Medical Center in Durham, N.C., said in a prepared statement.

The findings, published in the June 3 issue of Neurology, may not mean relief is coming soon for Parkinson’s sufferers, at least in the United States. In March, the U.S. Food and Drug Administration refused to approve the drug, calling evidence of its effectiveness insufficient. The drug’s manufacturer, Kyowa Pharmaceuticals Inc., has suspended development of istradefylline in North America.

The study was supported by Kyowa Pharmaceutical.

Istradefylline is a novel drug approach to Parkinson’s. The disease is usually treated with medications that work on dopamine, but their effectiveness wears off after time. Istradefylline appears to connect with receptors other than dopamine to open communication with the brain.

“Istradefylline and other agents in the same class that work in a different area of the brain are an important step forward when treating patients who experience this wearing off phenomenon and side effects related to dopaminergic drugs,” Stacy said.

Source: http://www.forbes.com/forbeslife/health/feeds/hscout/2008/06/02/hscout615943.html

Functional Electrical Stimulation Improves Walking

Wednesday, June 4th, 2008

Walking DemonstrationThis morning I read about a study that showed that functional electrical stimulation of the peroneal nerve via a neuromuscular stimulator has helped Parkinson’s patients improve their walking.  After receiving the electric stimulation researchers conducted a couple of tests to measure their results.

The first test consisted of walking 20 meters and the turning around.  Without functional electrical stimulation the average time was 35.6 seconds and with functional electrical stimulation 29.1 seconds.

The second test consisted of how far Parkinson’s patients could walk in three minutes.  For those with out functional electrical stimulation they were able to walk on average 110.5 meters and then with functional electrical stimulation they were able to walk 122.8 meters.

The research for was conducted with only seven people so k their feedback is a very small part of the Parkinson’s population.  Further research is planned with a larger group to support the findings.  We’ll keep our fingers on this for you, check back soon!